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Mean CapG expression levels in tumor specimen and normal tissues differed significantly (P < 0.027) indicating the putative oncogenic function of CapG in ovarian carcinomas.
Four 1.0-mm-diameter cores consisting of matched tumor specimen and normal epithelial samples were retrieved from selected regions of a patient's donor block.
Four 1.0 mm diameter tissue cores, consisting of matched tumor specimen and normal epithelial tissues, were retrieved from formalin-fixed, paraffin-embedded tissue blocks and arrayed on a 38 × 25 mm recipient paraffin block using a manual tissue arrayer MTA-1 (Beecher Instruments Inc., Silver Spring, MD).
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We analysed the predicted ontologies of the 338 gene set which overlapped between ovarian cancer specimens and normal ovarian surface epithelium and found over-representation of processes involving protein folding, cytoskeleton, cell cycle and cell adhesion (Table 7).
MTC and PTC specimens and normal thyroid tissues were obtained from 22 patients, who provided written informed consent to participate in the study according to the ethical guidelines of our Institute, after surgery.
We further measured the expression of miR-18b in NPC specimens and normal nasopharyngeal epithelial tissues.
To achieve this, we obtained proliferating hemangioma specimens and normal human skin tissues for comparisons.
These findings were similar in both cadaveric specimens and normal volunteers.
1α-hydroxylase protein was demonstrated in 79% and 100% of breast cancer specimens and normal breast, respectively.
In this study, we first examined the expression of TPX2 in human pancreatic cancer specimens, and normal pancreatic tissues.
We further investigated Notch1 protein expression in ICC specimens and normal control liver tissues using immunohistochemical analysis.
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