Applying the techniques described here renders it possible to process small postmortem brain specimens further, allowing detailed analysis, which can ultimately be registered back into MNI space without scanning whole brain specimens.
The conjunctival specimen was sent for histopathological analysis, which revealed evidence of marked damage to the lamina propria collagen, with mild regenerative atypia in the overlying epithelium.
It is our experience (Wessels et al, 2002; Van Beers et al, 2005) that a proportion of archival specimens appears unsuited for aCGH analysis, which is troublesome because array comparative genomic hybridisation (aCGH) experiments are tedious and expensive.
The evolutionary analysis, which compared the specimens with similar ones in South America, meant there was a small window between 100m and 105m years ago when an ancestor of the two dinosaurs must have crossed over land from South America, through Antarctica, to Australia.
One additional reason for not recovering mycobacteria from pathologic specimens may be the extended period (time) between collection of specimens and submission to the laboratory for analysis, which has been shown to reduce the likelihood of successful bacterial isolation [ 10].
Moreover, fresh material is required for RNA/DNA analysis, which disrupts the surgical specimen, potentially compromising morphological diagnosis, assessment of surgical margins of excision and staging.
The geometry of the specimen was based on coating quality and stress analysis, which are both discussed in this study.
These results were further confirmed by immunohistochemical analysis, which also showed apparent upregulation of PHB in 241 BC tissue specimens.
DIC is a method based on digital image analysis, which provides full-field, spatially continuous measurement of displacements across the surface of the specimen.
The hydrophilicity analysis, which was obtained by measuring PBS contact angle, showed that the E1 and E2 specimens had a contact angle of <5°, whereas the M specimen presented a contact angle of approximately 59°.
