If each new amino acid incorporated into the nascent coding system (and its corresponding mutant tRNA) eventually became specified by a different sequence (in other words, by a different codon), then each combination of tRNAs would have bound a unique complementary proto-mRNA, giving a one-to-one relationship between proto-mRNA and peptide.
The Cas9-sgRNA ribonucleoprotein complex precisely generates double-strand breaks (DSBs) in eukaryotic genomes at sites specified by a 20-nucleotide guide sequence at the 5′ end of the sgRNA that base pairs with the protospacer DNA sequence preceding a genomic protospacer adjacent motif (PAM) (Sternberg et al., 2014).
The protein Cas9 alters the DNA at a location that is specified by a short RNA whose sequence matches that of the target site.
In contrast, the "point" centromeres of Saccharomyces cerevisiae are specified by an ∼125-bp sequence that is occupied by a single centromeric nucleosome (Furuyama and Biggins 2007) and attaches to a single spindle microtubule.
The time varying nonlinearities of each node are modelled to be randomly switched between two different nonlinear functions by utilizing a Bernoulli distributed variable sequence specified by a randomly varying conditional probability distribution.
The GP.Dantu glycophorin is specified by a hybrid gene whose N-terminal sequence is encoded by the GYPB gene and C-terminal sequence by the GYPA gene.
The data processing system is protected through parity sequences specified by a high rate real convolution code.
These sequences are grouped into batches (or jobs) for efficient searching with Exonerate in step 2. 2) run_probe_search takes the set of sequences specified by a particular job, searches them against the target genome, and parses the Exonerate output results, storing the hits, including their scores, location, and masked sequence content (as ascertained from the soft-masking) in the database.
Genome editing was democratized by the discovery and adaptation of Cas9, an enzyme that can be programmed to cut target DNA sequences specified by a guiding RNA molecule (Deltcheva et al., 2011; Jinek et al., 2012; Cho et al., 2013; Cong et al., 2013; Jinek et al., 2013; Mali et al., 2013c).
The sequence of moves is specified by a series of the characters h, j, k, and l, where h = left, j = down, k = up, and l = right.
