Further, the fact that the association was observed under specific susceptibility models and was consistent with conditional logistic regression analysis might be suggestive of the specificity of the finding.
4 The different serotypes can be further classified according to receptor specificity, antiviral susceptibility and nucleotide sequence identities.
However, the lessened risk for cognitive decline experienced by physically active individuals with the APOE 4 gene, offers strength to the notion of causality, in regard to specificity of susceptibility [ 66, 71].
Various criteria can be used to distinguish between these midbrain dopamine neuron subtypes including morphology, protein expression, target specificity and susceptibility to death in Parkinson's disease and animal models thereof.
This suggests that when sex-specific susceptibilities are present, the sex-specificity varies from drug to drug.
Microbiological specificities (penicillin susceptibility and concomitant bacteraemia) have no significant impact on organ failure and mortality.
The only milestone that could be achieved by these drugs is to do with its pharmacokinetics, with extended plasma half-life, but not fibrin specificity or inhibitor susceptibility (Longstaff and Thelwell 2005).
Our final SNP models for ALS and PD had high model concordance and R2 values, and the sensitivity and specificity of the susceptibility model for ALS were 94% and 94%, and for PD were 92% and 92%.
One caveat regarding analysis of PVL in small animal models is a demonstrable species specificity of toxin susceptibility; for example, human cells have been reported to be 10-fold more susceptible to PVL-mediated lysis than mouse cells in vitro [34].
However, several limitations are associated with H2DCF-DA, including a lack of ROS specificity and its susceptibility to oxidation by different species such as peroxynitrite, nitric oxide, superoxide, and H2O2 under various experimental conditions (Crow 1997).
In this study, we uncover a pattern of virus and host species specificity in the filovirus susceptibility of bat cells, which can be explained by changes in the affinity of the essential interaction between NPC1 and the filovirus entry glycoprotein, GP.
