Sentence examples for specificity requirement from inspiring English sources

210, 1807 1821 (2013).These studies shed new light on the way in which peptide-MHC ligands can act as coagonists in the response to foreign peptide MHC complexes, though showing that the TCR specificity requirement in recognition of a coagonist depends on both TCR and CD8 coreceptor affinity for the agonist ligand.

Arguing, inter alia, that requests for access to archives reveal logical inconsistency with specificity requirement.

As Messina was supplied a minimum specificity requirement of 90% when these data were analysed, and this probeset could not satisfy this condition, it was rejected by Messina.

Even though some differences in the level of binding to various terminal Gal structures by C. jejuni 11168-GS grown at conditions that mimic mammalian and avian hosts were noted, there appeared to be no significant specificity requirement for a particular glycosidic linkage or underlying sugar.

In order to achieve a PPV of 10% for detecting serous EOC among BRCA1 mutation carriers, a test must achieve a specificity requirement of 78.1% at 80% sensitivity given the incidence of serous ovarian cancer over age 50 in this population is approximately 3000 cases per 100,000 [6].

These enzymes can differ in structure, molecular weight, substrate specificity, requirement for Ca2+, cell localization, and mechanism of action [ 2].

Like all pharmacologic agents they would be subject to meeting the administration, distribution, metabolism, elimination (ADME) and toxicology, drug interaction, and specificity requirements required for approval by pharmaceutical agencies worldwide.

The two classes of substrates exhibit different specificity requirements.

Hoerter, J.A. et al. Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC.

Hori, S., Haury, M., Coutinho, A. & Demengeot, J. Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.

In vivo, this methylation is sufficient to protect the host DNA from cleavage by the cognate restriction endonuclease, R.EcoP15I, because of the stringent cleavage specificity requirements.