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The best tests for specificity rely on mimicry by targeting SMOH with RNA interference (RNAi), the use of insensitive SMOH mutants and pathway epistatic analyses.
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High detection specificity relies on the design of specific probes and the elimination of nonspecific binding on the sensing surface.
Comparison with the Pol II system suggests that promoter specificity relies on a distinct "bendability" and "meltability" of the promoter sequence that enables contacts between initiation factors, DNA, and polymerase.
One molecule of decoron interacts with four to six collagen molecules, and the binding specificity relies on a large number of hydrogen bonds and electrostatic interactions, primarily with the collagen motifs KXGDRGE and AKGDRGE (d and e1 bands).
Instead, the specificity relies on the formation of the RNA static ring of appropriate size to fit on to the contour shape of the connector.
Data related to certain autoantibodies and their disease specificity relied on old technology and on studies published several decades ago that may be outdated and may need revision.
In this context, specificity relies on a versatile usage of conserved short linear motifs (SLiMs), which, surprisingly, often restrains the interaction potential of Hox proteins.
These results support the model that the ElxP specificity relies on the complete D-L-x-x-Q-T1/S1 sequence motif.
However, as data were only available from children who were referred from vision screening, analysis of NPV, sensitivity and specificity relied on utilising data from both eyes of each child, taking into account the correlation between the two eyes.
In P. anserina genesis of new allorecognition specificities relies on the combination of the DNA shuffling of a large repertoire of repeats between expressed and non expressed loci and a step of selection for advantageous new variants.
DNA-binding-specificity relies on amino acids within the α-helix reaching into the major groove of DNA [ 18].
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