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This suggests that they are important for the process of effector activation, but not necessarily for effector specificity recognition.
Although the recognition between SCR and SRK has been demonstrated at the molecular level, the regions of these molecules important for specificity recognition have remained elusive.
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Alternatively, catalytic domains tailored for high-specificity recognition of a Z-site central sequence might be desirable for applications where it is essential to minimize off-target reactions, such as gene therapy.
We demonstrate that this target-binding mechanism can improve both the affinity and specificity of recognition as opposed to classic probes solely based on Watson Crick recognition.
This specificity facilitates recognition of a broad array of microbes but introduces the potential for recognition of self-nucleic acids.
Moreover, the specificity of recognition may offer a unique opportunity to develop a (per chlorate-specific biosensor using per chlorate-specific from A. suillum that avoids interferences from nitrate.
There are many scenarios that describe the specificity of recognition between resistance proteins and avirulence proteins.
Curative treatment requires expanded T cells with exquisite specificity of recognition between normal and malignant cells.
This format of detection shows more sensitivity and specificity for recognition of target nucleic acid compared with homogenous format [38].
Enhancing the specificity of recognition, in the sense of discrimination between competing targets, is therefore expected to increase the fitness.
This mutation might therefore also disturb the specificity of recognition of a set of promoters relevant to carcinogenesis, or even induce an ectopic modulation of heterologous targets.
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