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Both, sensitivity and specificity reach their maximal value of 1.0 (Fig. 14) at the previously determined optimal similarity threshold at t = 0.46.
The best cut-offs points for CRP, DD, and PCT were 7.8 mg/dl, 1616 ng/ml and 0.3 ng/ml, respectively; but, neither sensitivity nor specificity reach 70% for any biomarker.
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> Specifically, the sensitivity exceeds 90% for deletions above 5 kb, while the specificity reaches 97%.
MDCT has very high sensitivity and specificity, reaching 98% and 100% accordingly for diagnosing aortic trauma.
In addition, the combined analysis of the two markers proved to be highly significant in the detection of colorectal polyps with a sensitivity and specificity reaching 71% and 95%, respectively, for the detection of advanced precancerous colorectal lesions.
How is this astonishing specificity reached?
Specificity reached 58% in women over 30 years.
The sensitivity and specificity reached to 95.31% and 98.55%, respectively.
In another study, if Lacrytest specificity reached 100%% [ 24], sensitivity was only 20%%.
However, when VP and greyscale parameters were combined, both sensitivity and specificity reached 100%.
Filters optimized for sensitivity reached at least 96.7% sensitivity and filters optimized for specificity reached at least 98.4% specificity.
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