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A comparison of the specificity patterns of the sera of patients from the 2 different districts among each other and with the sera of patients from the respective other district reveals no correlation, again emphasizing the individuality of the serospecificities in responses to LD.
The blots were developed with the same amount and dilution of serum in each case so that the different overall intensities of the signals reflect the different overall anti-LD serotiters, and the presence and intensities of the individual antigen bands the differences in the specificity patterns of the individual immune responses.
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As illustrated with the results presented herein, proteome serology is a powerful and highly resolving technology that provides an overall inventory of the antigenicity of the infectious agents and of the specificity pattern of the immune responses against complex pathogens.
All peptides that were phosphorylated by JH1-JH2WT and JH1-JH2V617F were also phosphorylated by JH1, indicating that JH2 domain limits but does not drastically change the phosphorylation specificity pattern of the JAK2 tyrosine kinase domain.
A comparison of the specificity patterns of sera from different patients reveals great differences in the antigens targeted.
Unbiased detection of off-target editing by adenine base editors in vitro uncovers differences in the specificity patterns of adenine and cytosine base editors, and of unmodified Cas9.
As such, some of the generalized biogeographic and host specificity patterns of Symbiodinium may simply reflect a gross under-sampling of endosymbiont communities in marine invertebrates [9].
The scFv 43M2 and scFv 51 epitope specificity patterns of binding to E7 were elucidated by Surface Plasmon Resonance (SPR) using a BiacoreX-instrument.
The selected dipeptide features are also analyzed and shown to play important roles in specificity patterns of PDZ domains.
Table 4 outlines the characteristic plasma antibody specificity patterns for each of the five immunogenic salivary protein sets.
These similarities of the specificity patterns with different isolates testifies to the reproducibility of the 2-dimensional electrophoresis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com