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Specificity of this system was tested by deleting each primary antibody.
Clinical samples of P. falciparum were used to determine the sensitivity and specificity of this system compared to microscopy and a nested PCR method.
We evaluate the dynamic range and specificity of this system in comparison to other available systems.
Finally, overall sensitivity and specificity of this system is 97 and 100%, respectively, using clinical samples (submitting).
These strategies dramatically reduced the off-target effects of the CRISPR/Cas system and will greatly improve the specificity of this system.
In addition, the identification, characterization, and optimization of Cas9 homologues or evolved variants may enable enhanced activity and specificity of this system.
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On the other hand, we show that the attachment step is crucial for the pronounced genetic specificities of this system.
In a series of tests, we evaluate the dynamic range and specificity of this Dual Drug Control DDCC) system in contrast to simpler systems, and note issues of particular importance for future tool development.
In addition, by using BSA, human IgA and human IgM as contrast, the excellent specificity of this sensing system for the detection of human IgE is also demonstrated.
The sensitivity and specificity of this test system is 84%and98%8%, respectively.
The spread of RNA viruses in eukaryotes that was accompanied by the displacement of the majority of DNA viruses [ 65] could have been the driving force behind the switch of the specificity of this defense system from DNA to RNA.
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