In addition to standard PMF bilinear modeling, more advanced factorization approaches have been applied to aerosol mass spectrometry data to improve the specificity and interpretability of the solutions.
To demonstrate the specificity of the developed UPLC method the solutions of CIP, MOX, NOR, OFL after photodegradation were analyzed.
Because of the specificity of the studied problem, the optimal solution has been found by finite element (FE) simulations.
When excess p-aminophenol and 4′-chloroacetanilide were added to the sample solution to check the specificity of the method the chromatogram presented the resolution of the acetaminophen peak from the related substance (p-aminophenol, and 4′-chloroacetanilide) peaks were equal to R S (P/PA) = 1.25, R S (PA/CA) = 2.76, R S (P/CA) = 3.73.
Although the previous studies have reported a number of RKIP ligands, they collectively lack definitive data regarding binding affinity, the location of the binding site(s) as well as the ligand specificity of RKIP in solution under near physiological conditions.
Given the specificity of the attached photobioreactor, a well-cultured seed solution should be initially inoculated onto an adherence membrane, and a culture may be subsequently prepared.
The ESI-MS measurement of the post-digestion solution confirmed the specificity of the enzymatic cleavage, whereas ToF-SIMS allowed for detailed surface analyses before and after the enzyme action.
The mass spectrometry analyses of the post-digestion solutions confirmed the specificity of the hydrolysis of the pentapeptide catalysed by trypsin (Fig. 5b).
The specificity of the method was ascertained by analyzing drug standard solution and samples of equivalent concentration (0.8 μg/ml).
