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Meta-analyses improve the sensitivity and specificity of the initial candidate set, integrating results from different, often publicly available datasets.
The final aspect of this study was to explore the potential for photochemical modification of the hydrogel network by exploiting the specificity of the initial tetrazine click reaction.
Once filtered to remove highly homologous sequences (>90% sequence identity), the relative specificity of the initial profiles was tested by scanning all included LmSIDER sequences with both HMM profiles using a global alignment algorithm (Additional file 2).
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Query limits applied to enhance the specificity of this initial search included the terms professional values, code of ethics, patient care, care delivery systems, management approach, decision making, professional relationships, interdisciplinary relationships, salary and compensation [ 24].
The importance of lymphocyte specificity during the initial recruitment of antitumor effector cells remains unclear.
Additional codes were then developed to reflect more detailed themes or constructs, thereby creating levels of specificity beyond the initial descriptive coding categories.
The advantages of meta-analyses are increased sample sizes and reduced experimental work, which help to increase the specificity and sensitivity of the initial biomarker.
In addition, we tested the tissue-specificity of 65 of the initial associations in skin fibroblasts, two of the initial associations in four brain regions, and one in SAT and VAT.
Instead, our data show that the temperature of the RT-reaction (50°C vs. 44°C) is more important in establishing specificity than the initial heat denaturing of the RNA.
Accordingly, this nonsignificant correlations were statistically different from the significant correlation between the temporal window of the illusion and IAF peak (all p values <0.03), confirming the specificity of our initial hypothesis, i.e., that individual alpha peak frequency is selectively linked to the temporal profile of the sound-induced double-flash illusion.
Determine, SD Bioline and Uni-Gold™assays had initial sensitivity of 100%9595% CI; 99.1 100) while the initial specificity of the Uni-Gold™ assay was 100%9595% CI; 99.6 100).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com