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As in other parts of the protocol recommendations, it is suggested to combine different fast imaging sequences to increase sensitivity and specificity of the examination [93].
If contrast medium administration is performed as a dynamic examination, the contrast medium enhancement curve can be reviewed and assessed for its enhancement pattern, further increasing the sensitivity and specificity of the examination [16].
NIRS can be acquired during dynamic contrast-enhanced MRI (DCE-MRI) to accomplish image-guided spectroscopy of the enhancing regions, potentially increasing the diagnostic specificity of the examination and reducing the number of biopsies performed as a result of inconclusive MRI breast imaging studies.
Whilst some of the advances facilitate lesion detection, such as full field digital mammography (FFDM) and computer-aided detection (CAD), others are aimed more at lesion characterisation and increasing the specificity of the examination with regard to the diagnosis of breast cancer, for example in ultrasound, magnetic resonance imaging (MRI) and nuclear medicine.
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The specificity of the clinical examination was high (95.8 %) thereby reducing unnecessary referrals for radiographic examination.
1) To classify the appearance of thyroid nodules displayed on ultrasound elastography; 2) to explore the sensitivity and specificity of this examination for differentiating benign and malignant nodules, with histopathologic analysis as the reference standard; and 3) to evaluate its utility for avoiding unnecessary procedures.
Study Selection: All articles that discussed the sensitivity and specificity of the physical examination maneuvers were extracted.
If severe dysplasia or carcinoma was considered to be the predictors of the presence of lung cancer, the sensitivity and specificity of the cytological examination of the sputum samples was 35.9% and 95.2%, respectively.
One small study found that when combined with an AST or ALT > 100 IU/L the specificity of the FAST examination was 98%%, suggesting a negative FAST and transaminases <100 IU/L should result in patient observation instead of abdominal CT scanning [104].
The sensitivity and specificity of the cytological examination for identifying subjects with high-grade ESD were 100 and 97%, respectively.
In the present study, the sensitivity and specificity of the clinical examination to identify a decreased LVEF were slightly higher (60%and83%3%, respectively).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com