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For codes and outcomes for which the validity is not known, random manual chart abstraction will be performed to compute the sensitivity and specificity of the code.
However, the specificity of the code was lower in patients with CKD than those without CKD (for all definitions of AKI).
For example, the specificity of the code for the RIFLE Injury definition was 82.6% (95% CI 80.7% to 84.4%) in patients with CKD and 96.2% (95% CI 96.0% to 96.4%) in patients without CKD.
Effects to our estimation caused by the poor specificity of the code were reduced using two methods: (1) years 2002 2006 were included as baseline as before 2006 intravitreal anti-VEGF treatments for ophthalmological use were not licensed; and (2) we crossed information of age with principal diagnosis.
The need for increasing specificity of the Code's terms was explained by one American civil society respondent: "It would be useful to have a clear objective in the WHO Code that relates to specific aspects of international recruitment.
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The specificity of the coding was greatly improved from 40% of cases coded to 163 (Malignant neoplasm of pleura) in ICD version 9 to 74% of cases coded to a mesothelioma code (C45) in ICD version 10.
Fourth, we collected ICD-9 codes from the one year pre- and one year post the date of spirometry, a time interval that may have reduced the sensitivity and specificity of the codes for COPD.
Second, the presence of an HCV diagnosis code on a medical claim is not necessarily positive presence of disease, whereby the sensitivity and specificity of the codes are unknown.
26 47 54 Between studies, there was no apparent relation between the specificity of the codes included and observed accuracy (ICD9 codes 998.5, 996.6 (or equivalent) vs a broader selection, data not shown).
Owing to the relative insensitivity but good specificity of the coding clusters, some adolescents who were classified in the accidents-only group may in fact belong to the adversity group, but did not have their adversity recognised or recorded.
Lydon-Rochelle et al. studied the accuracy of the reporting of particular maternal in-hospital diagnoses and intrapartum procedures in the state of Washington, USA [ 19]; however, the sensitivity and specificity of the coding of the conditions that we studied in this particular dataset are unknown.
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