Sentence examples for specificity of the aptamer from inspiring English sources

The flexibility of the described design allows for sensor specificity change through altering the specificity of the aptamer.

Aptamer beacon is a promising technique to resolve this problem by combining the excellent protein binding specificity of the aptamer with the sensitive signal transduction mechanism of the molecular beacon.

In the presence of the target, SiO2@Au-apt 1-target-apt 2-Cy3 sandwich-like complexes form due to the high affinity and specificity of the aptamer for V. parahaemolyticus.

The specificity of the aptamer to AFM1 was investigated in adjacent of AFM1 and aflatoxin B1.

To further confirm the specificity of the aptamer for immunohistochemistry, we performed peptide blocking.

Scale bar, 100 μm. Figure 5 Specificity of the aptamer by immunohistochemical staining.

On the other hand, the enantio-specificity of the aptamer variant in the ligand recognition was not enough to selectively detect d-adenosine over l-adenosine.

The effector specificity could be rationally changed by changing the specificity of the conjoined aptamer: when a mutation was introduced into the anti-theophylline aptamer that led to discrimination against theophylline and in favor of 3-methylxanthine (that also differed from theophylline by a single methyl group), the aptamer became solely responsive to 3-methylxanthine in vivo.

The aptamer-based THMS presents distinct advantages, including high stability, remarkable sensitivity, and preservation of the affinity and specificity of the original aptamer.

The specificity of the designed aptamer was investigated by AFB1.

The specificity of the MMP2 aptamer produced during the present study was confirmed in vitro and ex vivo.