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For these reasons, it was difficult to evaluate the sensitivity and specificity of the algorithms.
A second aim was to identify possible factors that impair the specificity of the algorithms.
The present work also confirms the high specificity of the algorithms (Table 2).
This might have introduced a verification bias in our study, slightly increasing the specificity of the algorithms.
Specificity of the algorithms among the 190 HAART-naïve patients alone was similar (median 95.5%, range 93.2 -- 100%).
In this regard, the diagnostic performance figures thus generated were of a preliminary nature, and the true diagnostic sensitivity and specificity of the algorithms remain to be established.
Similar(48)
The trade-off to this method is that the algorithmic detection can become overly broad, and the specificity of the algorithm is lowered.
The specificity of the algorithm was also not satisfactory, since we obtained a value of 98.8%.
The benefits of using these prediction algorithms are dependent on the capacity to increase the effective proportion of causative variants, which is highly dependent on the sensitivity and specificity of the algorithm used.
The sensitivity and specificity of the algorithm to diagnose smear-negative TB in HIV-positive TB suspects was 58.8% (95%CI: 42.2%–73.6%) and 79.4% (95%CI: 74.8%–82.4%) respectively.
The specificity of the algorithm in classifying consultations as being respiratory-related exceeds that previously reported.
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