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Further studies with larger number of patients should be performed to evaluate the feasibility, sensitivity and specificity of TCS in the detection of hydrocephalus in adult patients after SAH.
It is used to predict the specificity of TCS interaction: Our results compare favorably to most available experimental results, including the prediction of 7 (out of 8 known) interaction partners of orphan signaling proteins in Caulobacter crescentus.
19 We found substantially lower values for sensitivity and specificity of TCS to diagnose IPD than reported in earlier studies, including our own.
The sensitivity and the specificity of TCS to detect a significant MLS (that is, MLS >0.5 cm in method 2 of the CT scan) were analysed with the ROC curve.
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The clinical specificity of holo-TC II, as opposed to its comparability against MMA, is unclear.
The organ specificity of metastatatic TC arrest is not only determined by the repertoire of available adhesion molecules expressed at the cells' surfaces but in addition is influenced by the histological architecture, the availability, and organ specific exposure of possible adhesion sites within the targeted organ.
Densitometry of the phosphor image indicated >98% ± 1.8% of [99mTc(CO)3]+ was bound to the His-tagged protein (α-CD33 scFv) after 1 h incubation, whereas <2% ± 0.9% was complexed 'non-specifically' to the non-His-tagged protein C2Ac (Figure 3). Figure 3 Specificity of [ 99m Tc(CO) 3 ] + to His-tagged protein was demonstrated via (a) SDS-PAGE followed by (b) phosphor imaging.
Controls for RNAi specificity included injection of Tc-Toll1 (Nunes da Fonseca et al., 2008), and injection of dsRNA for the empty vector multiple cloning site (224 bp, pBluescript SK+, Stratagene).
To assess the specificity of the immobilization method, increasing concentrations of TC-tagged M probes ranging from 2.5 to 25 μM were directly attached to the four non-modified plastics by UV.
While most of the remaining TCs do not overlap other TCs on the opposite strand, a substantial fraction (21%) of TCs have overlapping TCs on the other strand.
Chiu et al. [ 7] reported an increased sensitivity of Tc-99m HSA of 96%, and a specificity of 100% in 26 patients.
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