Sentence examples for specificity of predictions from inspiring English sources

Existing methods can be effective but suffer from low specificity of predictions, which can reduce the willingness of experimental biologists to act on the results.

Additionally, the sieve effect of sequential application of three SVMs aided in increasing the specificity of predictions, which we consider more important than sensitivity at this stage of the search for unknown candidate miRNAs and their selection for experimental validation.

Most prediction methods are based on searching for known sequence motifs, and though many different approaches have been investigated to improve the apparent low specificity of predictions [3], there is still a lack of a common reference dataset on which to judge and compare a method's prediction performance.

QSLiMFinder uses specific query protein information to restrict the motif space and thereby increase the sensitivity and specificity of predictions.

To what extent can the specificity of predictions regarding structure-function relationships be improved by comparisons of related proteins?

Indeed they can exploit both knowledge bases (increasing the specificity of predictions) and raw data (for novel predictions).

Binding sites with a seed length longer than 10 bp (arguing for a high specificity of prediction) also only have been predicted for exon 6a, 6b and 7-3, with exon 6a exhibiting the highest number of these high seed length predictions.

Combining individual criteria that are independently predictive of essentiality increases the specificity of prediction - for example, a C. elegans gene selected at random is only 16% likely to be essential, whereas C. elegans genes that lack paralogues and have essential orthologues in S. cerevisiae and D. melanogaster are 81% likely to be essential.

Deng et al. [10] have attempted to infer DDIs from a small number of two-hybrid interactions in yeast (Y2H), using association rules and maximum likelihood estimations (MLE), resulting in low specificity of prediction.

If these variants, which were likely to be neutral, had been included, the specificity of prediction would be expected to decrease, thereby the relative performance of FWCST and FWBST compared to other tests would be improved.

To test the specificity of prediction of miRNA target sites, we first did experiments with a luciferase activity assay to test: a) the effects of miR-106a and miR-106b on Construct II; and b) the effects of miR-15b and miR-16 on Construct I.