We first tested whether stimulus related information carried by patterns (i.e., stimulus specificity of patterns) depends on the choice of the timescale at which patterns are investigated.
Figure 2A depicts specificity of patterns computed with two integration time constants (1 ms and 20 ms) for responses evoked with drifting sinusoidal gratings.
By manipulating the integration constant and computing the specificity of patterns, one can identify the optimal timescale on which information is best encoded, i.e., the optimal timescale for a given set of stimuli.
The three classifiers relied on the following features, respectively: combinations of mean firing rate (mean rate classifier), the specificity of patterns irrespectively of where in the trial they occur (specificity classifier), and the time-specific position of the patterns within the trial (trajectory classifier).
Classification performance is a non-linear procedure that gives a measurement of the ability of a classifier to separate samples from a given set into their true classes, based on a particular feature (e.g., mean rate, specificity of patterns, trajectory in pattern space).
To the best of our knowledge, this is the first study to use pattern analysis methods to investigate the spatial specificity of patterns of brain volume loss in relation to diabetes duration and HbA1c.
However, in the context of homomorphic patterns, which involve descendant edges, the concept of superpattern is not sufficient for capturing the specificity of a pattern.
A number of studies have used quantitative measurements to establish the specificity of atrophy pattern noted in PSP, and tried to differentiate from idiopathic parkinson's disease or MSA-P [24].
The specificity of this pattern is further underscored by the fact that both increased and decreased peaks of acetylation and DNA methylation are observed throughout the region.
Furthermore, to verify the specificity of this pattern of correlation between mOFC and TPO source activity, we examined the relation between the mOFC and other ROIs.
To ascertain the specificity of the pattern of staining, we aimed to verify these findings with several independent antibodies.
