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As higher concentrations were selectively attained by fibroblast-specific deletion of Sod2 (Treiber et al, 2011), these data underscore the specificity of our model and a previously unreported critical role of increased concentrations in suppressing the IGF-1/AKT axis in vivo.
The sensitivity and specificity of our model using 0.01 as the threshold is 100%and20%0% respectively.
The comparison of our model to ERPIN 3.1, using our test sets and following the protocol described by the authors [ 9] confirms the higher specificity of our model.
To address the specificity of our model, we also examined the reverse direction of whether capitalization support and relationship quality predicted changes in social anxiety symptoms over time.
Through combining serum ferritin and MS spectral data, the sensitivity and specificity of our model for prewarning severe aGVHD before transplant increased to 90.0%.
We want to compare the sensitivity and specificity of our model with MAPEs when there are multiple gene sets including both non-enriched and enriched sets.
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The high sensitivity and specificity of our models described in this study implies its usefulness in predicting drug-likeness of a molecule.
The fact that all five variants have been reported to be neutral variants in the literature [ 5- 7, 9, 11- 14] validates the sensitivity and specificity of our models.
Considering the specificity of our models, a cutpoint of 5 µg/L could be useful for exposure classification in an epidemiological risk analysis concerning arsenic levels in water supply in our study area.
Skeletal muscle and heart are among the most studied human tissues, and thus are appropriate examples to test the specificity of our models, which are based solely on genome-wide expression experiments.
As a whole, these results emphasize the importance of two specificities of our model: the modeling of drift moves as a complement to shift moves and the non-constant ρ that provides a simple adaptive method to account for the variation of affinity between probes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com