Sentence examples for specificity of methodology from inspiring English sources

These very low levels of noisy signal ensured the high specificity of methodology of eight-color MFC.

Although the association of the luminal phenotype with Tamoxifen and ESR1 expression level provides an additional validation of the specificity of the methodology, a more pressing question in the context of breast cancer therapy is the basal phenotype since effective treatments for this group of patients are limited.

Third, the retrieval performance to measure sensitivity and specificity of the methodology filters was not tested.

Controversially, both studies [ 48, 53] using MS-MLPA reported methylation of BRCA2 in a sizeable number of tumors, and this casts doubt on the specificity of this methodology.

We show a remarkable overlap between age-related DMRs from the same stage of the life course in multiple data sets, attesting the specificity of our methodology.

We also constructed a negative dataset (a benchmark dataset is not available for such studies) to assess the specificity of the methodology.

It is essential to generate additional data in larger studies in order to test the validity of this proteomic approach to preimplantation aneuploidy detection and to define the real sensitivity and specificity of this methodology.

The specificity of the methodology was validated (1) by the use of neutralizing anti-receptor antibodies, which block the ligand-binding site on the receptors; (2) by the use of an irrelevant ligand (PDGFB); and finally (3) by performing kinetic analyses that showed disappearance of the PLA spots with time, in conjunction with ligand-induced internalization of receptors.

The main specificity of the proposed methodology lies in the algorithm for calculation of stress histories in the stirrups and in the web concrete.

It is also difficult to distinguish low grade dysplasia from non-specific reactive or inflammatory changes due to the low sensitivity and specificity of current diagnostic methodologies.

Both the sensitivity and the specificity of signal amplification methodologies are dependent on the design of the target recognition sequences.