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Reproducibilty and specificity of method was determined by statistical analysis.
This increases the rate of false-positives and thus reduces the specificity of method (1) compared with method (2), which explains the metaregression findings.
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Overall, caution is warranted when performing validation trials with dideoxy-sequencing as the golden standard to determine the specificity of methods with higher mutation detection efficiency on FFPE-DNA templates.
Sequencing analysis of amplicons allowed us to verify the specificity of methods.
It must also be admitted that NO detection methods are often inadequate and that the accuracy and tissue specificity of methods used for measuring in planta NO production can be questioned.
Depending on the sensitivity and specificity of methods used to identify orthologous genes, the fraction of genes without orthologs between species is variable, and also depends on the quality of the genome assembly [ 40, 41].
The high degree of variability reported in the literature in the magnitude of apoptosis may be due to the diversity and specificity of methods used to quantify apoptotic nuclei.
The program was applied to compare sensitivity and specificity of methods for TFBS prediction based on P-values computed for Bernoulli models, Markov models of orders one and two and HMMs.
Whether variations in display efficiency affect a particular screening method is determined by the detection sensitivity and specificity of that method.
The specificity of the method presented here is to use a fully multi-parameters equivalence method.
The specificity of the method was confirmed by sequencing.
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CEO of Professional Science Editing for Scientists @ prosciediting.com