Sentence examples for specificity of interaction from inspiring English sources

Since we showed that the clones selected above could bind specifically to C. albicans cells, we decided to test the specificity of interaction in more stringent conditions.

As is evident from the results in Fig 1C, INr-1 interacted with Rev 53 67 peptide but not with the Rev 13 23 peptide, while INr-2 interacted with Rev 13 23 but not with Rev 53 67, indicating specificity of interaction.

The design of therapeutic compounds targeting transthyretin (TTR) is challenging due to the low specificity of interaction in the hormone binding site.

The main goal of these studies is to understand the nature of the specificity of interaction between drugs and nucleic acids, taking into account the interaction of the individual components with water molecules.

Kinetic experiments show the multiple binding modes of HD1 and NU172, which both interact with multiple sites of thrombin with low nanomolar affinities and show little specificity of interaction for prothrombin vs. thrombin.

We have explored this robust biosensor platform to study the interactions of carotenoid-binding proteins and their carotenoid ligands to assess the specificity of interaction, kinetics, affinity, and stoichiometry.

To validate the specificity of interaction, we observed that the interaction between β-TRCP1 and ZNRF3, but not RNF43, was impaired when the substrate recognition domain of β-TRCP was mutated to R474A (Figs. 2C and S1D) (Wang et al., 2015).

The mechanism by which the upstream sequences affect the specificity of interaction remains unclear.

This finding was not expected a priori because FNR and Fld are enzymes with different properties regarding kinetics and, most probably, specificity of interactions with endogenous cellular components.

However, phosphorylation in this region of p53 appears to be dispensable for the activation of some gene transcription by p53 [24], [24], although it may affect the specificity of interactions with other proteins.

Further sets of experiments were performed to reveal specificity of interactions of TBPs with DNA sequences.