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Wu RA, Collins K. Sequence specificity of human telomerase.
Kadam, S. & Emerson, B.M. Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.
In this paper we offer a disease module-based approach towards understanding the tissue specificity of human diseases.
Washietl, S., Kellis, M. & Garber, M. Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals.
Although some disease genes are expressed only in selected tissues, the expression patterns of disease genes alone cannot explain the observed tissue specificity of human diseases.
Vesia, M., Prime, S. L., Yan, X., Sergio, L. E. & Crawford, J. D. Specificity of human parietal saccade and reach regions during transcranial magnetic stimulation.
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LSTc and LSTa were used to probe the glycan specificity of human-adapted HAs from the Asian H2N2 pandemic of 1957 58 (andlbany/6/1958; Alb58) and the H1N1 "swine flu" pandemic of 2009 (A/California/04/2009; CA/California/04/2009
These findings offer an accurate and self-consistent formalization of tissue-specificity of human disease modules15, offering the graph-theoretical underpinning of relating diseases to specific tissues, consistent with the numerous empirical and experimental studies1,2,9,10,11,12.
Binding and cleavage specificities of human Argonaute2.
Jolma, A. et al. DNA-binding specificities of human transcription factors.
We have sought the structural basis for the differing substrate specificities of human glutathione transferase P1-1 (class Pi) and human glutathione transferase A1-1 (clAlphalpha) by adding an extra helix (helix 9), found in the electrophilic substrate-binding site (H-site) of the human class Alpha enzyme, at the C terminus of the human class Pi enzyme.
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