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One question embodied in the terminological distinction between promiscuous proteins (non-specific) and hub genes (functional) is the specificity of function itself.
exhibited distinctive performance profiles in these three versions of the Stroop task, providing further support for topographic specificity of function within the human ACC.
Other transport proteins and transport-related enzymes in gills, including a Na+/H+ antiporter, carbonic anhydrase, and Na+/K+/2Cl− cotransporters (Bianchini et al. 2008; Pequeux 1995; Henry et al. 2002; Towle et al. 1997, 2011; Serrano and Henry 2008; Jillette et al. 2011; Ahearn et al. 2004; Wheatly 1999), might be involved in the specificity of function.
Their specificity of function may also reside in particular affinity with some partners, like GEF.
The second missing constraint in the vector world has to do with specificity of function.
The model described here serves as a novel tool for protein annotation by predicting the specificity of function, based on the GO hierarchy, which may be shared between two proteins for a given level of sequence similarity.
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The unique structural features of Osh proteins explain the diversity and specificity of functions in PI(4 P-coupled lipid transport optimized in membrane contact sites.
Overall, our data provide an unprecedented analysis of the mechanisms determining, at different levels, the specificity of functions of paralogous MTs, suggesting clues to how these could have been achieved through evolution.
Therefore, we prioritized the links between these compounds and each biological function by considering the specificity of each function.
To examine the specificity of OLFM1 function in the chick heart, siRNA specific for OLFM1 (OLFM1 siRNA) was incubated with stage 15 chicken AV canal explants.
Sequence conservation of functional residues is therefore less obvious for residues that modulate the specificity of biological function.
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