Sentence examples for specificity of drug from inspiring English sources

However, in vitro characterization of these delivery systems remains a challenge in part because the critical performance indicator is colonic specificity of drug release.

Herein, we report on the effect of mismatches, sterics, and electronics on the rate and specificity of drug and probe release in both two and three component model systems, and on the stability of the prodrug linker in human serum.

We used the cell line H1975 expressing both the L858R mutation of EGFR as well as the T790M EGFR resistance mutation as a control for specificity of drug action.

Furthermore, the near-ubiquitous expression of glutamatergic receptors in the brain may hamper the specificity of drug development.

Geneticin was included because its inactivation by the APH(3′) enzyme allowed to control for the specificity of drug action.

Suggestions to improve the specificity of drug safety alerts such as patient-tailored drug safety alerts can be embraced by the term 'context'context

The specificity of drugs for retinoblastoma cells can be improved by targeting a mannose receptor overexpressed at their surface.

Biological replicates of HCT116 control cells and drug-treated cells showed a very high similarity (Figure S2A, B, C), confirming the technical robustness of the array and the high specificity of drug-induced methylation patterns.

The PDK1-IFPC::IFPN-AKT1 complex provides a cell-based platform to examine specificity of drugs targeting PI3K pathway components.

The homologous mammalian ribosomal proteins carry Gln-87 (humitochondrialribosomessores) or Gly-87 (human cytoplasmic ribosomes) in part accounting specificity of drugs for prokaryotic ribosome [7].

The specificity of drug-induced release was assessed by the addition of inhibitors mazindole (10 μM; for DAT and NET), paroxetine (10 μM; SERT), and tiagabine (10 μM; GAT1) to the test compound.