Sentence examples for specificity of delivery from inspiring English sources
The development of drugs through protein engineering is discussed as is the use of antibody drug conjugates to improve specificity of delivery to target.
Targeting of therapeutic agents to molecular markers expressed on the surface of cells requiring clinical intervention holds promise to improve specificity of delivery, enhancing therapeutic effects while decreasing potential damage to healthy tissues.
The use of NPs as vehicles for drugs enhances the specificity of delivery and decreases the minimum amount of NPs necessary for attaining and maintaining the therapeutic effect, thereby reducing the eventual toxicity.
Identifying the antigen(s) and improving specificity of delivery are goals of future studies.
The clinical application of potentially effective biological therapies for common acute cardiac conditions, like myocardial infarction, has been limited by efficiency and specificity of delivery of therapeutic agents.
In addition, it increases the efficacy and decreases many of the side effects by improving the specificity of delivery to the tumors, reducing absorption by normal tissues, compared to doxorubicin.
Although this assertion requires further confirmation, the possibility remains that tissue-specificity of delivery could be improved by using homologous tissue exosomes.
Therefore, the understanding of different principles of drug and gene delivery is necessary and needs to be taken into account according to the specificity of their delivery to tumors and/or normal tissues.
The desired selectivity in gene expression can be achieved by increasing the specificity of gene delivery or by controlling gene expression with tumour-specific promoters, such as α-fetoprotein or carcinoembryonic antigen.
While reliance on the EPR effect for tumor targeting has proven adequate for vascularized tumors in small animal models, the efficiency and specificity of tumor delivery in vivo, particularly in tumors with poor blood supply, has proven challenging.
In order to examine the delivery of active mammalian membrane protein using liposomes as carriers, we used a human carcinoma cell line HeLa which is negative for gp91phox proteins (data not shown) so as to exclude cellular specificity of the delivery.
