Exact(7)
For SCC, the 'high specificity' list included codes that are commonly and specifically used in the literature to identify SCC, which include unspecified disease of spinal cord ICD-9-CM code 336.9 and HCPCS codes specific to relieving pressure or decompression of the spinal cord.
For PF, the 'high specificity' list included only ICD-9-CM Codes (733.1X) that specifically indicated "pathologic fracture" on the claim, whereas the 'high sensitivity' list used codes indicating a pathologic fracture or "other fracture" to maximize the identification of all fractures that may have occurred due to cancer.
The 'base case' RAD definition used the 'high specificity' list of codes.
The 'base case' SCC definition used the 'high specificity' list since many of the procedures in the 'high sensitivity' list were not specific to SCC treatment.
The "alternative" SRE definition included codes identified under the 'high specificity' list of PF and codes under the 'high sensitivity' lists of RAD and SCC (in addition to all BS codes).
Thus, based on such assumptions, our 'high specificity' list for radiation to bone included ICD-9-CM and HCPCS codes indicating delivery of 2D or 3D external beam radiation therapy (EBRT) and radioisotope use.
Similar(53)
In summary, the "base case" SRE definition included codes identified under the 'high specificity' lists of RAD and SCC and codes under the 'high sensitivity' list of PF (in addition to all BS codes).
Because the control also indicated two positions (one in hrcU and one in XpsD), we cannot exclude the possibility that the residue differences correlated to tissue-specificity listed above are chance events.
Other MSA specificities listed were a few percent each and antibodies to aminoacyl tRNA synthetases (ARS) other than Jo-1, such as PL-7, PL-12, EJ and OJ, were not found.
In addition, since the Delvotest SP-NT appeared to lack specificity, a list of antibiotics was set up containing the positive LC-MS/MS results and those for which there were more negative than positive Delvotest SP-NT.
We might have objected to this strategy for this reason: because action-types can be specified in remarkably various ways and at remarkably different levels of specificity, no list of just or unjust action-types could be comprehensive.
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