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RNA interference approaches offer the possibility of rational design with high specificity, lacking in many current drug treatments for various diseases including cancer.
The chemical showed excellent specificity, lacking effects on PDGF receptors, ATP receptors, Ca2+ release, TRPC1/5 channel-dependent Ca2+ entry, STIM1 clustering, non-selective cationic current evoked by store depletion and the entire mechanisms of α-adrenoceptor-mediated vascular contraction.
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However, medical applications of these ligands remain a challenge due to low affinity, low specificity, lack of serum stability, and immunogenicity [19], [22], [23].
However, they have some drawbacks, including high background noise, extended time and labor requirements, lack of specificity, lack of sensitivity, and a high entry and operation cost.
However, due to oversensing of myopotentials and subsequent AF misdetection, specificity is lacking.
Despite structural insights into LexA, a detailed knowledge of the enzyme's protease specificity is lacking.
However, unlike light microscopy, which has the advantage of excellent fluorescence labeling specificity, EM lacks powerful and easy labeling strategies.
However, these autoantibodies are lacking specificity for IgG4-RD and are not known to be of the IgG4 subclass [13].
In general I found the Introduction lacking specificity.
Electrical signaling is the fastest, however, it is lacking specificity and an efficient de-exciting control.
The items designed to measure specific errors may lack specificity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com