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Optimization of assays for the detection of events in which the specificity is maintained at >95%.
Our results further highlight the fact that heteroclitic peptide-based immune interventions require careful evaluation to ensure that wildtype antigen specificity is maintained in vivo.
High specificity is maintained at 94% and 97% for nodal and patient based diagnoses, respectively.
However, the specificity is maintained in the heterotetramer because of the L subunit.
It was also noticed that induction treatment specificity is maintained even at the level at which precursor proteins are processed.
With 400 putative E3 ligases encoded by the mammalian genome, the receptor specificity is maintained by these proteins and hence, are heavily exploited by viruses.
Similar(52)
Removal of block 1 (construct 375c) led to 3-fold reduction in activity, while beta cell specificity was maintained in this construct (data not shown).
This specificity was maintained even as grasps were performed.
By comparison the same threshold performed far worse in the N0 sub-group with a sensitivity of only 16% although the high specificity was maintained.
If we combined macro- and microvascular risks, 73 of 376 cases (19.4%) and 187 of 1,372 noncases (13.6%) were newly classified as a high-risk population, and sensitivity increased up to 46.3% while specificity was maintained at 75.4%.
Briefly, strand specificity was maintained by the incorporation of deoxy-UTP during second-strand cDNA synthesis and subsequent destruction of the uridine-containing strand during the following step of library construction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com