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Our results demonstrate that this first-generation porcine oligonucleotide array is informative and the specificity is high.
For M. tuberculosis, specificity is high (98.5%) and sensitivity of 82.6% matches the line-probe assays from which our resistance panel was constructed, but still is below that of the gold standard of DST based on solid (Löwenstein Jensen) culture.
The absence of S. pneumoniae antigen in the urine from controls suggests that the specificity is high.
Tables 6 and 7 illustrate that the classification of cytotoxic molecules as expressed by the sensitivity is again low, but the specificity is high.
With the original cut-off for toxicity (pIC50 > 5.5) the sensitivity is low (0.08) and the specificity is high (0.92); this model yielded a 61% correct classification by predicting the majority of compounds to be non-toxic.
As shown in the left plot in the first row, the specificity is high when normalizing the profiling data of beads array by the four normalizers; however, the sensitivity is low.
Similar(35)
At a cut-off score of 8, the sensitivity is higher than 50% and the specificity is higher than 70%.
According to previous studies the specificity of u-PSA is poor7, but in our study we show that by using sophisticated computational techniques the sensitivity and specificity are high.
Specificity was high, but sensitivity, PPV and NPV were all low.
Specificity was high for definite (99%) and definite plus probable (83%) criteria, but sensitivity was poor at 18% and 51%, respectively.
Sensitivity varied between Sheffield (Northern General Hospital: 82.1%; Royal Hallamshire Hospital: 83.3%) and other sites (Doncaster Royal Infirmary: 71.4%; Newcastle's Royal Victoria Infirmary: 50.0%) whereas specificity was high (92-100%).
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CEO of Professional Science Editing for Scientists @ prosciediting.com