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We next asked the question if this relative specificity is due to specific structural epitopes formed by the different fusion proteins and we also wanted to explain cross-reactivity.
Structural studies reveal that this specificity is due to Met1-specific Ub-binding sites and a mechanism of substrate-assisted catalysis where a residue in a Met1-linked chain directly participates in the organization of the catalytic triad of the enzyme.
The specificity is due to a set of cell-surface glycoproteins called cell adhesion molecules (CAM).
The lower specificity is due to 36 false-positive cases.
We believe that this enhancement in specificity is due to a more "open" protein structure, in which the now accessible canonical target can compete effectively with adventitious cleavage sites of related sequence.
An important question is whether this specificity is due to the immune response rather than some other interplay between host and parasite genotypes.
Similar(46)
The lower specificity was due to 3 healthy dogs that were consistently miscalled when included in the test set (Additional file 1: Table S1).
The fluctuations in specificity are due to changes on the same time scales in the variance of the ED utilization signal.
This high sensitivity and specificity was due to the fact that this is the only work in the literature in which all PCa patients were studied before any treatment was initiated.
We tested the hypothesis that the observed decline in specificity was due to cross-contamination between sputum specimens during the splitting procedure by comparing sensitivity and specificity of the sputum test over time in the 83 specimens that were not split on day 1, and were tested without CPC on days 4 and 7.
It is possible that this non-specificity is due to a failure to disrupt the motor lip representation without disrupting the adjacent tongue representation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com