Exact(19)
Thus, these 3 patients were considered to have multiple specificities in their first available sample and were included in the multiple specificity group for analysis.
The mean age of the specificity group was 22.96 ± SD 5.78 (min, max: 18, 53).
A putative E3 is always assigned to the highest specificity group exclusively.
Columns with more than 10% gaps overall or with a specificity group containing more than 30% gaps are not considered.
We used PCR to molecularly characterize isolates by spa type, multi-locus sequence typing (MLST), agr specificity group, and virulence genes.
We use a zero-one functional similarity matrix with all pairs of proteins in the same specificity group receiving a one.
Similar(41)
There are different agr specificity groups that produce specific AIP that competitively inhibit heterologous agr activation and therefore virulence.
Here we describe the computational pipeline used to build a dataset of over 400 alignments of homologous enzyme domains each consisting of two specificity groups with columns likely important for specificity, as well as specificity groupings, identified.
Sequences in a cluster are assigned to specificity groups according to their fourth-level EC number, which corresponds to their specific substrate.
A set of proteins within a family that, as described above, share a specific function that is not common to the entire family have been called specificity groups (Mirny and Gelfand, 2002).
In view of this finding, the original classification of caspases into three specificity groups needs to be modified, at least for caspase-8, which tolerates small hydrophobic residues as well as the acidic residue Asp in subsite S4.
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