Exact(8)
A final pharmacophore filter was set up in MOE [11] to look specifically for compounds that can make these interactions that confer CDK2 specificity (Figure 8A).
The immunohistochemistry with pre-immune serum for anti-D1 receptor showed no specific staining pattern in the pre-feeding stage, demonstrating the antibody specificity (Figure S2).
CCPA, a specific A1R agonist, was less effective than CHA, an A1R agonist with lower specificity (Figure 3D).
Each substrate was recombined by the ZFR whose zinc finger domain was specific for the Z-site sequences, but not by the ZFRs with different specificity (Figure 4A).
The receiver operator curve (ROC) was used to determine this relation, retrieving a level of 2309 ng/L and showing an 80% sensitivity and an 86% specificity (figure).
Interestingly, integrating the analysis of the miRNAs with cytology offered a higher sensitivity than did any single approach used alone (71.8% vs. 61.5%; 71.8% vs. 35.9%, all P < 0.05), while having 93.0% specificity (Figure 3). Figure 3 Comparison of miRNA biomarkers and sputum cytology for lung cancer diagnosis in 39 patients diagnosed with stage I NSCLC and 42 cancer-free individuals.
We had established an excellent accuracy of BT to predict outcome (AUC = 0.93) by ROC analysis using our previously compiled internal BT measurement database: identification of P-DIE mice (BT ≤ 28°C) had 94% specificity, while identification of P-SUR mice (BT ≥ 35°C; at least for the next 24 h) displayed 100% specificity (Figure 1C).
The nuclear isoform (QKI-5) did not co-localize with Ago2 demonstrating isoform specificity (Figure 4A, 4B).
Related(1)
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