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Conversely, as the criteria are relaxed, sensitivity improves while specificity diminishes.
The presence of commercially available immunoblots with low specificity diminishes the value of the immunoblot as a confirmatory test [ 8].
Our conclusion is that although sensitivity remains an important attribute, using realistic information and values for sensitivity and specificity diminishes the influence of both attributes on preferences.
It is thus not surprising that lead's toxicity is not specific to the brain and we do not believe this lack of target organ specificity diminishes the inference for a causal relationship between lead and cognitive dysfunction.
Similar(55)
We postulate that this mechanism will generate pathway specificity and diminish unwanted cross-talk.
We discuss mechanisms for class-specific segregation of the MCPs in the cell membrane, which serve to maintain pathway specificity and diminish crosstalk.
Although RbAp48 exhibited a unique H3-binding specificity that is diminished with H3K4me3, RbAp48 is unlikely to account for observed specific binding of H3 tail peptide by NURD since it is also present in the Sin3A complex that does not to bind H3 peptide (Also see Figure 3).
In addition, Calcium phosphate precipitation (CPP) has been proven to be a fast, economical, and simple enrichment technique [37] in exchange for diminished specificity.
For example, retinotopic specificity can be diminished when the proportion of easy to hard trials is high, such as when multiple short staircases, instead of a single long one, are used during training.
Available blood assays for venous thromboembolism (VTE) suffer from diminished specificity.
Thus, any improvement in the sensitivity of documentation of comorbid psychopathology among suicides, rendered by the NVDRS, likely means diminished specificity.
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