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The B-locus is also involved in the formation of zygotes in that the alleles present at this locus in the encountering gametes of different sex specificity determine their probabilities of fusion.
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Li et al. [ 56] call these specificity-determining residues (SDR); Kalinina et al. [ 35] refer to them as specificity determining positions (SDP).
Specificity determines the ability of correctly excluding a melanoma.
Task specificity determines the most significant changes in cerebral blood flow in different mental rotation paradigms.
The structure reveals that ERα binds SMYD2 in a U-shaped conformation with the binding specificity determined mainly by residues C-terminal to the target lysine.
This specificity determines the host range of a virus.
The primary specificity determining residue (the P1 Arginine) points toward the body of the serpin and is unavailable to the protease (Figure 7).
We rely on previous prediction of 22 specificity determining residues (SDRs) in OR proteins [25].
These species-dependent differences in specificity determined in vitro are shown to correlate with the epitope repertoire recognized in vivo.
Arguably, such a model, trained using a much larger and more diverse data set, could potentially better depict subtle sequence-related specificity determining features.
The residues of a protein at these sites are called specificity determining residues (SDR) which when mutated lead to changes in the protein's function.
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