Taken together, our results indicate that Hq mice replicate the main features of RCCI deficiency in humans, including tissue-specificity, course, and interindividual variability.
The specificity and course of immune responses determine the physical manifestations.
This study revealed several novel findings related to the effects of antibodies from patients with anti-NMDAR encephalitis, including the lack of neuron subtype specificity, time course of the effects, fate of internalized receptors, and homeostatic responses to NMDAR loss.
The mechanism, tissue-specificity, and course of mitochondrial diseases are poorly understood [6].
Here we investigated the antigen- and epitope-specificity, magnitude, course and type of antibody responses following human experimental RV16 infection.
In order to overcome this obstacle, we designed experiments to study the functional dynamics of the BaMV RdRp in terms of its activity and specificity during the course of infection.
ICW and WB data were comparable regarding signal linearity, signal specificity, and time course of phosphorylation response to OT. ICW and WB yield comparable biological data.
Measures of sensitivity and, in particular, specificity, are of course completely dependent on the test data used.
In this study, we present several findings relevant to assessing the contribution of DNA methylation to tissue specificity during the course of normal and abnormal development.
These replacements may have contributed to the emergence of a new binding specificity and independent course of evolution of this subfamily.
Although a similar set of allergens to those eliciting responses from populations in western regions has been proposed 9, 11– 14, the course, specificity, and complexity of the allergic response in tropical countries may differ substantially from that in temperate zones.
