Sentence examples for specificity causes from inspiring English sources

The error in sensitivity and specificity causes concomitant errors in the area under the curve.

There are a few immunosuppressive peptide drugs already on the market or in the clinic (e.g. cyclosporine, sirolimus, tacrolimus), but lack of specificity causes severe or even life-threatening side-effects.

However hidden specificity caused by specific life history [ 30], and also possible conflicts of interest in VAM, can be taken on consideration as potential sources of selective pressure.

These distributions in their classical forms do not take into account CM structure practically possible specificity caused by the peculiarities of signal processing (SP) system.

They target presynaptic nerve terminals with high specificity, causing a severe disease termed botulism.

Although the function of both proteins remains unknown, the differences in immunoreactivity could suggest divergent functions or expression patterns or differential antibody specificity caused by glycosylation.

This finding might be either due to the higher sensitivity of CMR compared to TOE or due to its lower specificity caused by respiratory motion artefacts during CMR.

Nevertheless, chemotherapies and gene therapies are limited by tumor resistance and a lack of drug delivery specificity causing systemic toxicity and other off-target side effects.

The Acvr1 R206H/+ knock-in mice show fidelity to the human disease and develop FOP, just as in humans, confirming a phenotypic specificity caused by the FOP (R206H) ACVR1 mutation (Chakkalakal et al., 2012).

On the other hand, while [F]FDG PET is a sensitive technique, it has a low specificity caused by uptake in non-malignant conditions such as benign thyroid nodules and thyroiditis.

When the true prevalence of exposure is low (e.g., less than 10%) small reductions in specificity cause substantial reductions in the risk estimates, whereas reductions in sensitivity have smaller effects.