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However hidden specificity caused by specific life history [ 30], and also possible conflicts of interest in VAM, can be taken on consideration as potential sources of selective pressure.
These distributions in their classical forms do not take into account CM structure practically possible specificity caused by the peculiarities of signal processing (SP) system.
Although the function of both proteins remains unknown, the differences in immunoreactivity could suggest divergent functions or expression patterns or differential antibody specificity caused by glycosylation.
This finding might be either due to the higher sensitivity of CMR compared to TOE or due to its lower specificity caused by respiratory motion artefacts during CMR.
The Acvr1 R206H/+ knock-in mice show fidelity to the human disease and develop FOP, just as in humans, confirming a phenotypic specificity caused by the FOP (R206H) ACVR1 mutation (Chakkalakal et al., 2012).
On the other hand, while [F]FDG PET is a sensitive technique, it has a low specificity caused by uptake in non-malignant conditions such as benign thyroid nodules and thyroiditis.
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Since sulfotransferases exhibit low substrate specificities caused by their high degree of conformational freedom [1], activity prediction is a challenging task.
We next assessed the magnitude of the specificity switches caused by these cancer mutations, by comparing the wild-type to mutant drift in specificity to the specificity differences observed between wild-type human kinases across the kinome.
Molecular modeling suggests that increased PI3Kβ specificity is caused by the interaction with salt bridge (Lys782 Asp923) and Asp862 that creat a unique pocket in PI3Kβ.
The slight increase in infections averted with a decreasing specificity is caused by the higher number of patients that are isolated based on a false positive test result and are therefore at lower risk of transmission.
The variant allele has been associated with lower in vitro activity and changed substrate specificity, possibly caused by a lower mRNA stability and protein folding [ 24, 25], whereas studies on intestinal mRNA levels and protein expression levels are not consistent [ 22, 26- 28].
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