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Sensitivity and specificity calculation for specific cutoff points was not performed because the sample size in our study was too small for the assessment of stable point estimates of the variable.
The accuracy of these variables was assessed calculating its area under the curve (AUC), assessment of the best cutoff value, sensitivity and specificity calculation as well as the likelihood ratios.
Since true negatives are unknown, specificity calculation is left as an open question.
The specificity calculation should therefore be: Specificity All other data analyses and the rest of the data presented are correct.
Eighty patients were assumed to be necessary for the feasibility testing in part B. We provide sensitivity and specificity calculation of CalproQuest based on CIs (figure 3).
Thus, in our final analysis we had a very small number of true-negative lesions, with a consequent bias in the specificity calculation.
Similar(52)
Sensitivity and specificity calculations based on optimal thresholds are similar to those calculated using a standard delta Ct threshold of 1.0 (compare Table 1 and Table S4).
Data analysis methods had a pronounced impact on assay sensitivity and specificity calculations.
As macrosomia was expected to be the most frequent undesirable foetal outcome, sensitivity and specificity calculations have been based on this outcome.
Results from the lesion area-based sensitivity and specificity calculations are presented in Figure 7.
Sensitivity and specificity calculations across the expanded validation panel were consistent with those obtained from the initial panel.
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