Suggestions(2)
Exact(3)
The best candidate ssDNA MRE had a K d value of 6.33 ± 0.58 nM and high specificity based upon flow cytometry analysis.
Interestingly, PglD shows a relaxed substrate specificity based upon its ability to also acetylate UDP-4-amino-4,6-dideoxy-β l-AltNAc, an intermediate along the pseudaminic pathway, which may allow for cross-talk between the two pathways.
Most of these results support the work of Olson and colleagues (4), although the fact that their system only detects small hemorrhages and microaneurysms is a serious limitation in our view, and sensitivity and specificity based upon the photographic interpretation by a single reader is unlikely to become widely accepted.
Similar(57)
A cutoff of 400 ng/ml has been demonstrated to be a high specificity threshold based upon international analysis that has been done on other data sets [ 21].
Sensitivity and specificity based on meta-analysis.
The sensitivity and specificity calculations were based upon spectral assignment to these criteria.
This is done by constructing time-specific ROC curves based upon estimates of incident sensitivity and dynamic specificity.
Based upon specificity and sensitivity analyses, a suggested cutoff PDUQp score for predicting MAVRD is provided.
It is thus essential to quantitatively infer the binding stability and specificity of such interaction based upon large-scale but low-accurate complex structure models which could be readily obtained from sophisticated molecular modeling procedure.
Although this probeset could be used to construct a classifier with a reasonably large margin, the presence of a sample of normal tissue with expression close to the cancer group drastically reduces the specificity of a classifier based upon this probeset.
Sensitivity and specificity for disease prediction based upon mutation status were 96 and 74 %, respectively.
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Justyna Jupowicz-Kozak
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