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The AUC was calculated by integrating the area between the ROC curve and the diagonal line where sensitivity is equal to one specificity based on the trapezoidal rule.
In comparison the NISSSA and the MESS presented a lower sensitivity and same specificity based on the same study group.
Still, there is a need to greatly improve both potency and specificity based on the current rather poor performance of cystatins in biotechnological applications.
This study investigated the effects of practice schedule and task specificity based on the perspective of adaptive process of motor learning.
We dichotomized values of creatinine (using a renal SOFA cut-off of 1.2 mg/dL) and endocan (best sensitivity and specificity based on the ROC curve) to predict need for RRT.
With LLE, mass spectrometry offered a small linear range of 20 60 μg L−1, but it provided specificity based on the mass-to-charge ratios (m/z) of the molecular ions.
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In this review, we summarize design strategies for generating proteins with desired sequences such as long contiguous base pairs and diverse sequence specificities based on the nature of Cys2-His2 zinc finger proteins.
However, this may be an overestimation of lineage-specificity based on the criteria used in the mapping pipeline.
Figure 2 illustrates a forest plot of estimates of sensitivity and specificity based on results of the 15 included studies and stratified by type of sample (isolate vs. clinical specimen).
Thus, the specific factor related to determining metal-substrate specificity, based on additional structural considerations in the N- and/or C-terminal ends of CsHMA3, requires further study.
The specificity, based on kcat/ K1/2m, and not taking into account the Hill coefficients for p300, reveals a preference for K18 > K14 > K23 > K9, with selectivity differences up to ∼2-fold.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com