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The AUC was calculated by integrating the area between the ROC curve and the diagonal line where sensitivity is equal to one specificity based on the trapezoidal rule.
In addition, an ideal carrier will have target tissue specificity based on tumor-specific receptors.
CsrA has a clearly defined specificity based on binding to a specific mRNA sequence to inhibit translation.
Thus, the specific factor related to determining metal-substrate specificity, based on additional structural considerations in the N- and/or C-terminal ends of CsHMA3, requires further study.
We developed an alternative approach for controlling binding specificity based on computational protein design.
This communication reports on a novel biosensor to study the hybridization specificity based on eriochrome cyanine R (ECR) monolayer film modified glassy carbon electrode (GCE).
In comparison the NISSSA and the MESS presented a lower sensitivity and same specificity based on the same study group.
Unipept32 is a web application that allows users to compare provided lists of peptides to the large non-redundant UniProtKB peptide database to reveal taxonomic specificity based on known peptide sequences.
Here, we report the development of a procedure to select protease variants with altered specificity based on the well-established Saccharomyces cerevisiae adenine auxotrophy-dependent red/white colony assay.
This website contains B1H screens of Cys2His2 zinc finger libraries, per-domain predictions of zinc finger DNA-binding specificity based on this data, and the domains from our data predicted to best specify each 3bp target.
Still, there is a need to greatly improve both potency and specificity based on the current rather poor performance of cystatins in biotechnological applications.
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