Sentence examples for specificity and selection from inspiring English sources

Given that the degree of substrate specificity exhibited by an RS is functionally coupled to the accuracy of protein translation, the RS is restrained by tremendous selective pressure; therefore, integration of structural approaches with directed evolution of RSs can expand upon our understanding of the evolutionary tenets governing substrate specificity and selection.

Cleavage site specificity and conformational selection in type I collagen degradation.

Daneshtalab, N., Dore, J. J. & Smeda, J. S. Troubleshooting tissue specificity and antibody selection: Procedures in immunohistochemical studies.

TGFβ receptor interactions alter ligand specificity and effector selection, offering a regulatory mechanism to calibrate TGFβ signaling based on the cellular microenvironment.

This proportion (16.3%) was significantly higher than that found in nonorphan 1 1 orthologs (753/8,997 = 8.4%), which indicates an association between gene lineage-specificity and positive selection (Fisher exact test, two-tailed, P < 0.0001).

This is a scheme that is known to enhance the signal specificity and precision of selection center localization (Grossman et al. 2010).

A second problem is that of tissue specificity, sample selection and annotation.

Here, we discuss the potential of ecogenomics approaches in developing high-throughput methods for detecting and monitoring organohalide respirers, and for providing improvements to selection, specificity and sensitivity of target biomarkers and their application to evaluate bioremediation strategies.

Initially, attention focused on specificity and affinity, with the selection of mAbs being based primarily on their ability to inhibit tumour cell growth in vitro.

NB-LRR genes regulate disease resistance [ 59] and most of these SNPs affect the leucine-rich repeat domain that confers pathogen specificity and is under positive selection in other NB-LRR proteins [ 60].

Environmental heterogeneity significantly increases the difficulty of predicting host and pathogen fitness-related trait variation as the environment may alter both selection specificity and strength (Lazzaro and Little 2009; Wolinska and King 2009), leading to variation in specific gene frequencies in nature.