Sentence examples for specificity and potency of from inspiring English sources

Dendritic cells direct the specificity and potency of cellular immune responses that can be targeted for cancer vaccines.

We also systematically analyzed the key residue sites, which may greatly influence the specificity and potency of TIL-type protease inhibitors.

The specificity and potency of proteins would enable them to be effective intracellular drugs, provided that the proteins are delivered efficiently to appropriate intracellular compartments within specific cell types.

The inhibitory data against the RTKs in this study demonstrates that methylation of the 4-NH and/or the 7-NH influences both the specificity and potency of RTK inhibition.

Recently, it has been shown that overexpression of Argonaute-2 (Ago2) can enhance the specificity and potency of shRNAs for mRNA targets with perfectly matched binding sites [42].

Notably, the presence of three disulfide bonds in domain 2 explains the rigidity, specificity and potency of this domain towards its particular cognate protease subtilisin.

Inconsistent serotyping results have been reported for other hybrids (10, 15 ) and may result from differences in specificity and potency among different batches of factor serum.

The design of bisubstrate analog inhibitors could provide for the enhancement of specificity and potency in protein kinase inhibition.

Thus, there is a large unmet clinical need for new anti-epileptic medicines with improved specificity and potency, and with new mechanisms of action.

In order to understand the mechanisms behind this sensitisation process we have used anisomycin, an agonist of the JNK pathway in mammalian cells, which is often used in studies involving JNK because of its specificity and potency in activating the JNK pathway.

For therapeutic purposes, it is thus unlikely that this class of molecules can become a class of viable inhibitors of ASM due to both specificity and potency issues.