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This suggests that use of isoform-specific HDAC inhibitors may increase the specificity and efficacy of these drugs in the treatment of psychiatric disorders.
Apart from providing insights into the disease process reporter mice harboring transgenes can also provide highly specific mechanistic information on the biological specificity and efficacy of therapeutic agents.
215 Moreover, the membrane of EMVs harbors donor cell-specific factors (eg, GPI-anchored proteins) that enable the EMVs to target specific acceptor cells for transfer of their mi/mRNA contents with exquisite specificity and efficacy.
The high specificity and efficacy of these nanoparticles were further reinforced by in vivo experiments [52].
The rapid rise of antibody-based therapies is largely due to their desirable safety profile, target specificity, and efficacy.
The greatest challenge in cancer treatment is to achieve the highest levels of specificity and efficacy.
This approach ensures specificity and efficacy in fighting cancer cells, while healthy tissues remain largely unaffected.
There have been a number of breakthroughs improving the specificity and efficacy of CRISPR/Cas-mediated genome editing.
To increase specificity and efficacy, we have designed a synthetic antioxidant, XJB-5-131, targetget mitochondria.
The five compounds selected for these tests based on their low potential toxicity, commercial availability and predicted potency demonstrated varying levels of specificity and efficacy.
Specifically, we highlight emerging in situ genome engineering approaches as tractable techniques to manipulate microbial communities with high specificity and efficacy.
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CEO of Professional Science Editing for Scientists @ prosciediting.com