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The simultaneous specificity and breadth of her appeal, across gender, race, and nationality based on her self-professed fans, is remarkable, and it took me by surprise the first time I started following her online.
Thermodynamic binding energy predictions, conservation and uniqueness scores must be computed for millions of candidate probes, in order to select an optimal combination of probes for each target gene family, balancing sensitivity, specificity, and breadth of coverage.
By using an improved memory B cell immortalization method [41], combined with high-throughput parallel screening with a panel of recombinant Env-based antigens, we isolated a panel of 58 human mAbs which we have characterized with regard to epitope specificity and breadth of neutralization.
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No significant interaction was observed between larval specificity and habitat breadth on butterfly density (ANOVA F 4,72 = 0.84, P = 0.505), and thus the interaction term was removed.
However, both larval specificity and habitat breadth had a significant effect on butterfly distribution (F 2,76 = 8.20, P < 0.001 and F 2,76 = 12.53, P < 0.001, respectively).
There was no significant interaction between larval specificity and habitat breadth on butterfly distribution (ANOVA F 4,72 = 1.32, P = 0.270), and thus the interaction term was removed from the analysis.
The relationships between the density and the predictor variables are depicted in Figures 6 and 7. To study the effect of niche breadth on the density of the butterflies, we analysed the effects of larval specificity and adult habitat breadth by ANOVA and Tukey's multiple comparisons test.
The relationship between distribution of the butterflies and both of the predictor variables are shown in figures 2 and 3. To study the effect of niche breadth on the distribution of the butterflies, we analysed the effects of larval specificity and adult habitat breadth on butterfly distribution using analysis of variance (ANOVA) and Tukey's multiple comparisons test.
First, they can readily provide well resolved data on performance and specificity, and thus niche breadth and overlap (Flores et al. 2011 Weitz et al. 2013).
Analyzing hospital characteristics across multiple specialties means sacrificing specificity for breadth, and this applies to all our hospital variables.
Factors such as gene expression level and breadth (tissue specificity), and the length of the encoded proteins, correlate with both network centralities and the likelihood of detecting positive selection (Anisimova et al. 2002; Lemos et al. 2005; Kim et al. 2007; Kosiol et al. 2008; Alvarez-Ponce 2012; Alvarez-Ponce and Fares 2012) and thus could also represent confounding factors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com