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We have conducted the specificity analyses of the identified markers against public microarray gene-expression data for other human diseases (http://bioinfosrv1.bmb.uga.edu/DMarker/) and obtained 106 genes whose differential expression are specific to ovarian cancer.
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CM performed the substrate specificity analyses of AtAPY1-GFP.
TRANSMODIS had successfully recovered a majority of previously known direct targets, i.e. the nine genes that were reported to be PHO-regulated prior to the study of Ogawa et al. Because we do not know the total number of true targets of Pho4p, it is difficult at the current stage to give sensitivity and specificity analyses of TRANSMODIS.
CAMERA's BLAST tool was used for specificity analyses of all 2226 probes against 9 environmental databases of assembled sequences, as well as "CAMERA's Non-Identical Nucleotide Sequences" database, the largest non-redundant database with 65 million sequences totaling approximately 207 gigabases.
To allow comparisons across measures, the cut-off values associated with greater risk for mortality based on sensitivity and specificity analyses of baseline values were determined (Table 2).
Substrate specificity analyses of Chi18H8 against three different-length analogs of chitooligosaccharides showed an activity of 113 U/mg protein for MU-NAG2 as substrate, and of 39 U/mg protein on MU-NAG3, but no activity against MU-NAG.
Specificity analyses measured the percentage of clients or residents without a relevant diagnosis indicated on the DAD or NACRS who were noted as not have the relevant diagnosis on the linked interRAI record.
Based on the results of specificity analyses in the literature [ 32] and BLAST [ 33] searches focusing on the bp1241 bp132626 region of the IS1111 transposon which failed to identify organisms other than C. burnetii with the specific targeted sequence, the specificity of the PCR was defined as 100%% for purposes of prevalence analysis.
Table 6 shows the sensitivity and specificity analyses to assess the prediction power of logistic regression models.
We also conducted sensitivity and specificity analyses to determine the ability of one urine sample or a pair of urine samples to predict long-term urinary BPA concentrations over several months.
Sensitivity and specificity analyses to assess the ability of one urine sample to predict a subject's exposure tertile are shown in Table 4.
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