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Model A using data available at the onset of the leading CRImild event identifies 80% of patients who will deteriorate to CRIcrit with 56% specificity and 100% such patients at 17% specificity, achieving area under the ROC (AUC) score of 78% (Figure 1).
The carrier has the capacity for large loads of anticancer drugs and is able to deliver these agents selectively to cancer cells with high specificity, achieving effective cancer cell death without inducing nonspecific toxicity.
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An initial validation study using COP to predict shock outcome from the patient data set resulted in a performance of 60% specificity achieved at 100% sensitivity on a blind test of the data.
The signaling specificity achieved by the activation process of GPCRs is determined not only by the lowest energy receptor state as in the crystal structure but also by the range of nearly degenerate conformational states that the receptor explores.
Similarly, any increase in specificity achieved by a shift to the right will be more than offset by a decrease in sensitivity.
Besides binding to the 5' untraslated region of a target mRNA with specificity achieved through base-paring between the two RNA molecules, sRNAs can also significantly down-regulate target protein levels, yet do not notably affect their target mRNA stability [11].
How, then, is Ybx1 binding specificity achieved?
In terms of specificity achieved, the Specificity Terms Filter again performed marginally better.
Is specificity achieved through association with distinct insulator partners at different CTCF sites?
However, innate properties of miRNAs limit the sensitivity and specificity achieved with this method.
We next wanted to assess the sensitivity and specificity achieved using panels of biomarkers.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com