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Binding and cleavage specificities of human Argonaute2.
Jolma, A. et al. DNA-binding specificities of human transcription factors.
We have sought the structural basis for the differing substrate specificities of human glutathione transferase P1-1 (class Pi) and human glutathione transferase A1-1 (clAlphalpha) by adding an extra helix (helix 9), found in the electrophilic substrate-binding site (H-site) of the human class Alpha enzyme, at the C terminus of the human class Pi enzyme.
The aim of this study is to define the ionizing radiation-related molecular specificities of human thyroid tumors developing in the radiation field of patients treated with radiotherapy.
The similarity in the binding specificities of human and mouse LSECtin suggested that, like the human protein, mouse LSECtin might be a target for binding to the surface glycoprotein of Ebola virus.
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Wu RA, Collins K. Sequence specificity of human telomerase.
Kadam, S. & Emerson, B.M. Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.
In this paper we offer a disease module-based approach towards understanding the tissue specificity of human diseases.
Washietl, S., Kellis, M. & Garber, M. Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals.
Although some disease genes are expressed only in selected tissues, the expression patterns of disease genes alone cannot explain the observed tissue specificity of human diseases.
Vesia, M., Prime, S. L., Yan, X., Sergio, L. E. & Crawford, J. D. Specificity of human parietal saccade and reach regions during transcranial magnetic stimulation.
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